So I have a bit more information to share about this situation. It is a rather technical summary but should be definitive for anyone coming across this product and wondering if it can be used with a TB or TB2 Mac. The quick answer: No.
The longer answer:
I have an Apple TB3 to TB2 adapter, OWC TB4 Hub and a TB4 SSD enclosure. Connecting them to the MP 6,1 without a reboot results in no enumeration. Rebooting the MP does cause a "partial" enumeration. The PCIe tunnel enumerates so I see the NVMe controller of the SSD connected to the PCIe bus. The NVMe controller enumerates with a link width of x4 and a link speed of 8 GT/s which is expected for the JHL 7440 TB controller which has a PCIe Gen 3 bus and which comprises the SSD enclosure. However, there is no Thunderbolt enumeration so I cannot see either of the Hub, the adapter, the TB2 cable or the TB4 cable. So, there is no way to tell from enumeration what the link speed is between the MP and the hub or the hub and the enclosure. I performed a speed test using the Blackmagic Disk Speed Test and the result suggests the link speed is only 10 Gbps (896 MB/s read, 851 MB/s write). Finally, the SSD volumes that were mounted before putting the computer to sleep were all ejected when the computer woke up thus support for power management is lacking.
So, you can get a connection to a TB3 device that has a PCIe endpoint, but it is likely not an intended and supported use case for the Apple adapter.
So, my conclusion is that the Apple adapter is not particularly useful when connected to a TB or TB2 Mac. I think it is intended to ONLY be used with TB2 devices and the suggestion that it is "bidirectional" is misleading. Apple's own overview suggests the adapter can be used with a dock:
The Thunderbolt 3 (USB-C) to Thunderbolt 2 Adapter lets you connect Thunderbolt and Thunderbolt 2 devices — such as external hard drives and Thunderbolt docks — to any of the Thunderbolt 3 (USB-C) / USB 4 ports on your Mac.
But it is the last part of the sentence that I think spells out the limitation: to any of the Thunderbolt 3 (USB-C) / USB 4 ports on your Mac. So, the adapter supports connecting a TB2 device/dock to a TB3 Mac but does not support connecting a TB3 device/dock to a TB2 Mac.



