According to Apple's own technical specifications, this laptop supports:
* USB 3.1 Gen 2 (up to 10Gb/s)
MacBook Pro (16-inch, 2019) - Technical Specifications
If you are going to choose USB3 devices, I highly recommend they also support the UASP protocol is it will help with data transfers. If you utilize any adapters, hubs, or docks, then make sure they also support the UASP protocol since every device in a direct link from the SSD to the laptop must support UASP as well. Plus if you connect any USB 1/2 items to a hub/dock, then these slower devices will not interfere with the USB3 transfers.
https://www.startech.com/en-us/blog/all-you-need-to-know-about-uasp
USB devices are much more common and are usually a lot less expensive than a device supporting the Thunderbolt protocol. Part of the decision depends on finances as well as how you will be utilizing the drive....some workloads may benefit from a Thunderbolt drive.
FYI, USB-C connectors & cables with a device does not mean the device supports the Thunderbolt protocol. USB-C is a connector type. Both Thunderbolt 3/4 and USB 3/4 utilize a USB-C connector. Make sure to check the product technical specifications and/or data sheets to confirm which protocols the device supports. If it is not clear, then most likely the device only supports the USB protocol.