Since you didn't provide us with which exact mouse brand & model:
If your mouse is not powering on with new batteries despite trying different types, there could be a few possible causes for this issue. Here are some troubleshooting steps you can try:
1. Check battery orientation: Ensure that the batteries are inserted correctly with the positive (+) and negative (-) ends aligned properly in the battery compartment. Sometimes, the orientation can be easily overlooked.
2. Clean the battery contacts: Over time, battery contacts can accumulate dirt, dust, or corrosion, which can interfere with the electrical connection. Use a clean, dry cloth or cotton swab to gently clean the battery contacts inside the mouse. Ensure that there is no debris blocking the contact points.
3. Reset the mouse: Some mice have a reset button on the bottom. Try pressing the reset button to see if it resolves the issue. If your mouse doesn't have a physical reset button, you can try turning it off and on or removing and reinserting the batteries.
4. Update mouse drivers: It's possible that outdated or incompatible mouse drivers could be causing the issue. Visit the manufacturer's website and download the latest drivers for your mouse model. Install them on your computer and see if it resolves the problem.
5. Try a different USB port: If your mouse is connected wirelessly via a USB receiver, try plugging the receiver into a different USB port on your computer. Sometimes, certain USB ports may have insufficient power supply or other compatibility issues.
6. Test with another computer: To rule out any computer-specific issues, try connecting the mouse to a different computer or laptop. If it works fine on another device, it could indicate a problem with your computer's USB ports or settings.
7. Contact manufacturer support: If none of the above steps resolve the issue, it's possible that there could be a hardware problem with the mouse. Reach out to the manufacturer's customer support for further assistance or consider getting a replacement if the mouse is still under warranty.