Thunderbolt 4 nvme drive issue on M1 Studio w/ Ventura 13.4

Hi all. Apologies in advance for the book.

I've had an M1 Mac Studio since the end of last year. I use it for Audio Production. I have been reliably using an NVME drive (APFS format) in a TB4 enclosure as my main audio drive since I bought it. It never gets removed (or even touched). All of the sudden about 3 days ago, the drive just disappeared from my machine. I did all the normal things - unplug/replug, try a new TB port, reboot, etc... It wouldn't show up - not in Finder, Disk Utility, or in the terminal. So I unplugged it and tried it in my Windows machine. Disk Manager saw all of the partitions. I was able to mount and browse them using an APFS driver. All of my data was there. I wiped the drive. I plugged it into my other Mac (an M1 Mini) and was able to format/mount it just fine in there. I also ran First Aid on it and it didn't find anything. I then took it back to my Studio - nothing. Same as before. I bought a new TB cable (a certified TB4 cable from OWC) and had the same results.

Fast forward to today. On a hunch, I take my Dell Thunderbolt 3 doc (that I use with my Linux laptop). I plugged it into one of the back TB4 ports on the Studio and then plugged the NVME enclosure into the TB3 port on the back of the Dell Dock. BOOM... It shows up on the Mac. So I unplug the enclosure from the dock and plug it directly into the Studio again... Nothing.

I'm convinced this is a software issue somewhere dealing with the Mac Studio hardware. I don't think it's a general Ventura issue because my Mini has the exact same OS rev and works fine. I have yet to reach out to Apple Support.

The only thing I haven't done yet is to buy a different enclosure and to try that, but I'd rather not if possible, since the TB4 ones aren't the cheapest.

Does this sound familiar to anyone?

Note - the NVME enclosure I am using is this one - a Bus powered one. https://www.amazon.com/gp/product/B0BB5W3QGQ/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&psc=1