WebKit and Canva are the two items using the most CPU, Memory, and Energy usage so you may want to check them out. Make sure all your third party apps are completely up to date. WebKit is Apple's browser engine which is utilized by many of Apple's built-in apps which utilize online resources.
It also appears the Adobe software is showing high CPU utilization as mentioned at the end of the EtreCheck report.
The EtreCheck report also mentions high memory usage so it is possible you don't have enough memory for the workloads at times. After using the laptop and you start encountering issues, check the Memory tab of Activity Monitor. If the Memory Pressure graph is showing yellow or red, then it indicates your laptop doesn't have enough memory for that workload. If the Memory Pressure is green, then check the "Swap Used" and "Compressed" memory values listed beside the pressure graph. If "Swap Used" or "Compressed" is showing GBs, then the laptop does not have enough memory for that particular workload. Try quitting some apps to give your main memory intensive app some more room.
You may also want to run Disk Utility First Aid on the hidden Container. Within Disk Utility you may need to click "View" and select "Show All Devices" before the hidden Container appears on the left pane of Disk Utility. Even if First Aid says everything is "Ok", click "Show Details" and scroll back through the report to see if there are any unfixed errors. If there are any unfixed errors, then try running First Aid from Recovery Mode, otherwise you will need to erase the disk followed by reinstalling macOS & restoring from a backup.
Also, OneDrive can cause performance issues due to how it accesses the files on the drive.
Keep in mind that when you are using another OS in a Virtual Machine, that it will definitely impact system performance because it will tie up CPU, memory, and storage resources. If you are using other system intensive apps, then you may want to close one while working in the other.