The second point says no need for additional drivers: https://www.hidglobal.com/products/omnikey-3021
Key Benefits
- Compatible with any smart card: It can be easily distributed together with any smart card, including credit cards, eID cards or software for other applications involving online banking
- Easy to install: With the USB CCID support, you can easily integrate it into an existing system by connecting the host and smart card reader. No need for additional drivers!
- Readily compliant: It can be smoothly integrated into a PC environment as it is equipped to meet all relevant industry standards
- Portable form factor: The unique size makes it an ideal reader for large-scale deployments and mass distribution
- Suits any application: It is compatible with virtually any type of contact smart card, application software and major PC operating system
But, "PC environment" generally means Windows, although a Mac is a personal computer.
The data sheet does say OS X. have you tried the device yet? If not, I suggest you try it and see.