I have the same question and spent time on the phone with Apple and they could not answer my question at all.
It is really unclear on the Apple web site that discusses the prescription requirements for the Vision Pro if it is best to use your full distance prescription so the focal distance is going to be distance or if something more middle distance is better:
Using Apple Vision Pro with vision prescriptions and vision conditions - Apple Support
There it says to not use computer prescriptions so I ordered my lenses with my -2.00 for distance and 1.25 ADD and the site said it would adjust it down to reduce eye fatigue and I cannot find any information that says exactly what mine was reduced to. Is it just a little, or all the way down to -0.75? Trying them out at the moment it feels to me like its just a bit too strong as I have a different prescription for computer work and with that I can see most middle distance stuff just fine. It is -0.75 mono vision.
Then the same link above has conflicting information because it says that if you need reading glasses, you can get reading glass inserts for the Vision Pro. Makes no sense if you can see fine in the distance? If you can see fine in the distance and need readers for close up work, then why would you ever need reading lense inserts for the Vision Pro?
So seems to me perhaps my computer prescription would have been better? Tempted to test the theory by ordering with by computer single lense prescription and see. But Apple and ZEISS were not able to answer it for me, and would not be able to tell me exactly WHAT my lenses are?
I have used it with my -1.75 contacts and it seems decent, but I wish I had my older -1.5 ones to try. But my contacts always dry out so I don't like using those and I have to have 1.00 readers if I have those installed to use the computer.