I agree there is an issue with the SSD, and that the BX500 has an unfortunate history, but I do not think it is failing. This:
Drives:
disk0 - CT2000BX500SSD1 2.00 TB (Solid State - TRIM: No) ⚠️
Internal SATA 6 Gigabit Serial ATA
Were it sick, this value shown in the resutls:
File system: 37.09 seconds
would likely be much higher, closer to the time-out value of 120 seconds.
In doing HDD to SATA SSD conversions, I found that, although fast when first installed, SATA SSDs start to slow over time to incredibly abysmal speeds if TRIMForce is not enabled. Been there; done that. Your SSD should be doing an minimum of 480-500MB/sec.
Before doing anything else:
1) Out of an abundance of caution, repeat the EtreCheck test with all external drives disconnected, especially the G-Tech USB-2 drive. I've seen reports like this here where some USB-2 external drives slowed overall performance. Not common, but easy enough to test.
2) If that does NOT return SSD speeds to the 480-500MB/sec range or better, BACK UP your drive before engaging TRIMForce BUT...
...DO NOT use the third-party TRIM enabler that is on your hard drive. Instead, use the Terminal method laid out in this article:
HOW TO EXECUTE ‘TRIMFORCE’ COMMAND WITH YOUR SSD
Speeds will NOT increase immediately. Restart the computer in SAFE MODE. Once you have a Safe Mode desktop, do nothing else except walk away. Let the computer sit unused in Safe Mode for about hour so SM can do its work. This will NOT erase your drive.
Subsequent tests may show little or no improvement right away/ So do the safe mode boot again and let it sit. It took about three of those, allow at least 30 minutes, before my Mac's responded to TRIM on an aftermarket SATA SSD installed.
NOTE: on my Mac, SSD speeds were excellent for about 2 years without TRIM but then plummeted. Today it is back to its speedy self.
CCleaner has to go. Earlier incarnations of it to were eager to flag important system files as junk and tell users to dump them.
Macs—cat-like— clean themselves, and have for over 20 years. Your paid Apple good money to create and implement elegant and automated self-maintenance routines that do all the housekeeping needed in the wee hours of the morning when most people don't use their comptuers. They even defrag.
The industry knows this. To me, that make any third-party products that claim to clean, optimize, tune-up, or otherwise play maid to your Mac a four-letter word that starts with "s."