What does this path mean on my MacBook Air?

Anaconda is used with to distribute applications using the Python programming language. It is installed on the User folder in that location. Depending on what you are doing to show this message, it may simply be expecting to find it at this location. More information about Anaconda and seeing that expression can be found here:

https://docs.anaconda.com/free/anaconda/install/mac-os/

You generally interact with it using Terminal or a program called Jupyter Notebook.