How can I disable and locate stolen iPad with only serial number?

An iPad cannot be located using just its serial number - but can be potentially located or managed using Apple's Find My service...

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Locate a device in Find My on iPad - Apple Support

Here is Apple’s advice for lost or stolen devices:

If your iPhone, iPad or iPod touch is lost or stolen – Apple Support

Use the Find My app to locate a lost or stolen device – Apple Support

If the Find My iPad feature was enabled prior to it being “misplaced”, then if active, you would stand a good chance of locating it. 

However, if the feature was not activated prior to being misplaced - or the iPad has been inactive or without a network connection for more than 24 hours, the last known location will not be available - and the opportunity to use technical means to recover or remotely manage the iPad may have been lost.

Be assured that nobody can gain access to your iPad without successfully entering the correct device Passcode presumed to be known only to you) - and for this, there are a limited number of tries before the iPad will automatically become disabled. As such a brute-force attempt to access the iPad, by guessing the correct passcode, is highly unlikely to be successful. Only if your device Passcode is known to whoever finds your iPad will any locally stored data be at risk of discovery.

iOS/iPadOS is architecturally designed to protect the owners data. 

All locally stored data is encrypted; by design, the only copy of the encryption keys necessary to access local data are held within the Secure Enclave - the device security chip. The device Passcode unlocks the Secure Enclave, which in turn releases the encryption keys to the Operating System while the device remains unlocked.

If an incorrect Passcode is repeatedly entered, the Secure Enclave automatically wiped and the device disabled - an operation that erases all stored encryption keys. This is known as a crypto-erase. Once erased, all locally stored data is permanently beyond reach and cannot be recovered.

You can’t locate it with the serial number. You would need to have had Find My turned on for the iPad in order to locate it. Otherwise you’re going to have to go old school and physically look for it which may be pointless if it was stolen versus misplaced.