What would happen if I change the region on my IPad
What would happen I change the region on my iPad will it affect my apps, and will anything get deleted, and can it affect the App Store
First note that that is not something you can idly do. You have to do certain preparation.
Yes, many things can be affected, particularly purchases. See Change your Apple ID country or region - Apple Support
"To make sure that you can access your previous purchases in your new country or region, redownload your previous purchases on every device on which you might want to view the purchase before you change your country or region." Subscription services have to be canceled and started again.