Well, it's a slow hard drive (5400rpm) which would explain why it appeared slow from the beginning. But the disk speeds reported are especially low, indicating some problem with either the drive itself or something getting in the way of disk access.
In that regard, something is using most of the RAM in your Mac but the report doesn't indicate what it might be.
I suggest removing Google Chrome (which is a known resource hog).
Also give Etrecheck full disk access (in Settings > Privacy & Security > Full Disk Access), then re-run Etrecheck and post the results; it should provide more detail.