Mac Mini (M4) loses wired keyboard and wired mouse connections upon sleep

I have a new Mac Mini M4 that I am using with a MacCally wired mechanical keyboard and wired mouse, whenever the system goes to sleep, it loses connection to the keyboard and mouse. To get it to come out of sleep mode, I have to unplug the keyboard and mouse and plug them back in to get the computer to respond to input so I can get it to wake up. Why do they loose power and then need to be unplugged and plugged back in to power them up?


This happens regardless of which USB ports they are connected.

Any help would be greatly appreciated. Thanks!

Mac mini

Posted on Jan 16, 2025 1:20 PM

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Posted on Jan 18, 2025 6:23 AM

Sleep is unnecessary on later Macs and should be disabled. Shut for long absences/idle overnights and for regular operation use the settings exactly as shown below: (reboot after setting):


Also, do not manual-sleep for brief absences; use instead the Lock Screen settings to switch the display off on timer:


Once set, you can also use Control-Command-Q to immediately lock your screen (instead of waiting for the display to switch off on timer).

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Jan 18, 2025 6:23 AM in response to FootbridgeFarm

Sleep is unnecessary on later Macs and should be disabled. Shut for long absences/idle overnights and for regular operation use the settings exactly as shown below: (reboot after setting):


Also, do not manual-sleep for brief absences; use instead the Lock Screen settings to switch the display off on timer:


Once set, you can also use Control-Command-Q to immediately lock your screen (instead of waiting for the display to switch off on timer).

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Feb 22, 2025 3:00 PM in response to FootbridgeFarm

I’m having the same issue, also with a Macally mouse. However, it’s not after sleep. It happens during normal use.


I was having problems with my Macally wired mouse (usb-c) losing power (the red light on the bottom was turned off). The device was about 2 years old so I thought it was going bad. So I replaced it with a new device of the same model. Within 15 minutes it’s done the same thing, while actively using the mouse.


Apple Mac Studio 2022, M1 Max. Running Sonoma 14.7.4


Were you able to find any other solutions to this?

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Mac Mini (M4) loses wired keyboard and wired mouse connections upon sleep

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