How-to create a desktop shortcut to enable / disable 'natural scrolling'?

On my Macbook Air with the inbuilt trackpad, natural scrolling is activated by default. (--> 'System-Settings', Trackpad, tab 'Scroll & Zoom', first slider = 'Natural scrolling')

To keep the same mouse scrolling direction together with my docking station & external mouse, I always need to go to Trackpad settings to manually disable 'Natural scrolling'.

It would be more convenient having a desktop shortcut for that particular setting so that I could enable/disable 'Natural scrolling' on one-click.

Is there any option and, if yes, any idea how to create that?

Thank you for your kind help!