I also have an M-Audio Keystation 49e, but the M-Audio/Evolution MK-449C and the MK-461C have many more MIDI control features, they are deluxe versions of the 49e. The 49e does not allow you to control any MIDI parameters except for modulation, pitch bend, volume, and a few other advanced functions. I started out with the 49e, but have now graduated to an Evolution MK-461C.