Itunes cannot run because some of the required files are missing. Reinstal

iTunes just prompted for an update and after completion I have the same problem. I am assuming that it has installed the wrong version so I will now try downloading 64 bit version and installing that. Seems poor that a simple software release should knock out iTunes though.

I downloaded iTunes again, ran install and selected Repair. This installed and all seems to be working. Assume that the automatic download selected the wrong version of iTunes. Poor anyway, it is not even a major upgrade. Hope this helps in some way.

You need to check that you have the right version of iTunes to download - 32 or 64 bit according to your operating system.

I had the same problem after an iTunes update about 3 days ago. I didn't have to uninstall/reinstall or even reset. I just did a Windows repair.
Control Panel -> Uninstall Programs -> in the program list, find iTunes, right-click and repair. Took about 1 minute, I think it flashed up two different boxes. Then I could open iTunes and it all worked as normal.

Amart111 you are a god!! I know zero about computers and was almost in tears when I had this problem. Saw your post, tried it out and all is now well in my life again!! Thank you thank you thank you!!

I just had heart failure till I read your post.
Worked as described. Thank you!

Same here. Did a reinstall ~ didn't work. Did a repair ~ didn't work. What can I do to make it work? Help!

Fearns is a legend he has the answer - When ITunes has the message
"iTunes cannot run because some of it's required files are missing."

Very frustrating and I notice threads like this dating back to 2006 so don't hold your breath for a permanent fix

It looks like a couple of methods work but this one is easiest for sure as descirbed by Fearns - I did it ans literally 2 mins later without a restart - Itunes is working as normal

1/ Open Control Panel
2/ Open Programs
3/ Right click on ITunes and select "repair" from drop down list
Windos reconfigures ITunes for a couple of mins and then Itunes is back

Yahoo!!