I will think twice before sycnign again
I highly recommend you remember to and sync regularly.
Shouldn't take more than few minutes after the initial backup.
When I first got my iPad, I sync'd two or there times then I pretty much quit using my computer as I used the iPad for everything.
However, after installing a bunch of apps, a few weeks later, I decided to sync to get them onto the computer. Something messed up and I had to restore the iPad, losing all the data I had on it.
Getting the apps back was no problem, though it was a pain.
Now I plug it in every few days just to make sure I have a recent backup and all purchases (apps and music) get copied over to the computer.