1. The answer above will work if the artwork has been downloaded from the iTunes store. If the files have embedded artwork then you can select the files, Get Info, and on the Info tab, put a tick against the empty white artwork box. Click OK and all artwork, embedded or otherwise will be removed. Rather than work with the whole library use a smart playlist with the rule *Has artwork is true*.
2. No. iTunes doesn't give you a feature to sort columns on one value, then sub-sort on another. Many of the built-in column sorts do work in a multi-valued way however. For example the Album by Artist ordering looks something like this in pseudo-SQL:
SELECT * FROM Tracks ORDER BY Sort Album Artist, Sort Album, Disc # (Empties Last), Track # (Empties Last)
+Where there is no Sort Album Artist value it is infered from Album Artist, Sort Artist or Artist. Where there is no Sort Album it is infered from Album.+
tt2