I am pretty sure Vuescan works with it. Vuescan 9 is really nice, and the support is excellent. Whenever I run into a problem, I email him and there is usually a new version in a day or so, and an email from Ed Hamrick asking me if it fixed it.
The Microtek drivers for other scanners might work, but may be buggy. With the improvements in Vuescan, I have given up on them.