Hi Trailerman,
You are correct in your understanding that the 2009 and 2010 Mac pros use a triple channel memory controller - memory slots 3&4 and 7&8 share the same channel.
However, in general there is only a very small decrease in performance using all 8 memory slots:
http://macperformanceguide.com/Reviews-MacProWestmere-Memory.html
A few applications, Photoshop CS5 in particular, will use all the available memory up to the maximum 64GB, but I am not familiar with Logic Pro or any audio software, because I use my system mainly for photo editing, digital imaging and colour printing up to A2 size.
If all the memory modules you install are 1333MHz, then your memory speed will not drop to 1066 MHz.
In my opinion you cannot have too much memory, but obviously cost is a major factor. If you start off with however many 8GB modules (in pairs) are within your budget now, then you can always add more (in pairs) in the future.
If I could afford to, I would upgrade to 64GB RAM, purely for Photoshop CS5, but when I upgraded from the original 6GB of Apple RAM, in November 2009, 2GB was the largest capacity sold by Kingston, and there was a lot of negative feedback at that time about the recently introduced 4GB modules from OWC and Crucial - in fact the latter's 4GB modules were still incompatible with some Mac pros as recently as a couple of months ago.
However, I find that 16GB (8 x 2GB Kingston RAM) is more than adequate for my general requirements.
From personal experience I can thoroughly recommend the Kingston brand, but at the moment they do not sell anything larger than 4GB modules, and so, if you decide to max out your memory, then I would recommend importing 8GB DIMMs from OWC.
I have used OWC on a couple of occasions, and both times I received the goods within 2 days via Federal Express, who then invoiced me for the VAT element plus a £10.00 Advancement Fee.
Lloyd Chambers' Mac Performance Guide is biased towards photography, and includes only a limited performance guide with Apple Logic Studio:
http://macperformanceguide.com/Reviews-MacProWestmere-LogicStudio.html
Possibly you are already aware of this website, but I will include it just in case you are not, because it has 50 pages of feedback from Logic users:
http://www.gearslutz.com/board/music-computers/371545-logic-pro-multicore-benchm arktest.html
Hope this helps,
Regards,
Bill