A workstation or server entering sleep mode does a lookup for a _sleep-proxy._udp DNS record to find a sleep proxy to answer Wake-On-LAN requests on its behalf (using the EDNS0 Owner option (4)) in case an important packet is sent to the sleeping machine.
Older versions of Mac OS X Server don't know how to handle opt 4 requests coming from workstations running newer versions of Mac OS X, so the bizarre packet is logged but no action is taken. The more Snow Leopard machines you have, the more your log will fill with "mDNSResponder: ERROR: getOptRdata - unknown opt 4 " messages. You may have noticed that these messages get more frequent during times when workstations are heavily used, and that they mysteriously disappear outside of business hours - the reason, of course, is that all your workstations go to sleep and aren't being woken up until a human presses a key or mouse button the next day. Laptops running on battery are usually set to sleep more frequently, so large numbers of mobile users will fill your 10.4 server logs.
As has been already stated, you can safely ignore this message...or upgrade to Snow Leopard or Lion Server to eliminate it completely.
The Wikipedia entry for Bonjour Sleep Proxy is a good place to start your reading on this issue:
http://en.wikipedia.org/wiki/Sleep_Proxy_Service