iPad 2 Sound Issues?

What is your side button set to do, mute or lock screen rotation? I know you said it's not muted, but did you check to see what the side button is set to do?

You're welcome.

I had the exact same problem today. I tried resetting volume and a factory reset with backup info. This did not work, and I did not want to lose my data.

Then I realized today was the first day I used the headphone jack. WIth headphones, I get sound on all applications. Without headphones, I experience the same issues as the original post; no sound in apps, sound on ipad, netflix, etc.

Is this possibly a switch inside the headphone port that isn't getting flipped when I remove the headphones?

I would appreciate any advice or suggestions so I don't have to reset as a new iPad.

I had problem and fixed by going to settings,general and toggling ringer alerts adjust with buttons. Now I get all sounds. I think a setting got stuck when updating but now it works either way after changing once.

I had the same issue, here's how I solved it without reinstalling. The mute button was flipped to "mute" when I repurposed the switch to "screen rotate lock." Apparently the iPad "remembers" this mute setting even though the switch has been repurposed to screen rotation lock. I changed the switch back to "mute/unmute", made sure I was in the "unmute" position, played some sounds, then repurposed the swith back to "screen rotate lock". This solved the problem for me.

BTW a good application to test with is TED.

You don't have to keep flipping the switch back and fore. If your switch is set to 'system sound mute' then your screen lock is in the multi-tasking area and vice versa,
To access the control in the MT area, double tap the home button, swipe to the right and there it is on the left.