2 HDD iMac & Bootcamp question

Hello,

If I have an iMac with 2HDD's, either 2 internal or 1 internal and 1 external, is it possible to setup boot camp with Windows booting off the secondary hdd and not the hdd with my OSX partition? If so, how? Looking at the support guide for boot camp it mentions to do that I would need to remove the drives of the lowered number bays but I'm not intending this setup for a Mac Pro.

Many Thanks!