Posting a reply to my own post in case anyone else finds this in a search...
Last night I installed the updates for all my apps. ("Update All")
I also sync'd my iPhone which gave me the 4.3.3 iOS update.
I'm not sure if its' just a fluke, but battery performance seems normal today. Hopefully it was just a bad app in there, but if the problem returns (I may not have the same things running today) I'll post back.