I don't think you're in safe mode.
On to the actual issue. Are you booted into OS X or Windows?
If Windows, I'm probably not going to be able to help.
If Mac, are you logged in to an administrator's account?
If so:
First check the S.M.A.R.T. status on your HD: Applications > Utilities > Disk Utility > in the panel at left, select the first item inthe list/your HD mechanism > look at the bottom of the main window next to S.M.A.R.T. status and see if it says “Verified” or something more ominous like“Failing.”
If it's Verified, then click on the Repair Permissions button and wait for it to finish. There will be a list of items it does not repair (for me, it's about 20 items).
After that, click on the Verify Disk button. Wait for it to finish.
If it says "appears ok" quit Disk Utility.
If it says your HD needs repair:
Boot from install disc (insert disc > restart > immediately hold down the c key and keep holding it until you see “Preparing Installation”) > at first screen select the language and click Continue > click on theUtilities Menu in the menu bar > select Disk Utility > select your HD in the panel on the left side (the name of the HD’s manufacturer and the model number, usually the top item in the list) > look at the bottom of the main window next to S.M.A.R.T. status and see if it says “Verified” (good) orsomething more ominous like “Failing.”
If S.M.A.R.T. status is "Verified," run Repair Disk > click Repair Disk at bottom of main window. Run this at least twice, and keep running it until it says “appears ok”twice in a row. If that doesn’t happen, you may need a stronger utility (such as DriveGenius, TechToolPro, DiskWarrior) or if the directory is damaged beyond repair, you may need to reinstall the OS, or you may have a damaged HD which will need to be replaced (repair utilities can only repair the directory structure, not the HD itself). When this is finished, quit Disk Utility, quit the installer, and restart. Once booted normally, go to Applications > Utilities > Disk Utility and run Repair Permissions.