I had the same problem. I've seen it pop up from time to time before 10.7 but it's been running near-continously after upgrading. I force quit VShield in the Activity Monitor. Then, poking around, I found the /usr/local/vscanx directory. This contains an unistall command which I exectued.
After force quitting in Activity Monitor, try the following in Terminal.app:
$ cd /usr/local/vscanx
$ ./VirusScan\ Uninstall.command
I saw the following:
VirusScan for Mac Uninstall
-------------------
This will uninstall VirusScan for Mac. If you wish to
proceed, authenticate below or close this window
if you wish to cancel.
Password:
Uninstalling VirusScan ...
Shutting down VirusScan Daemons...
Cleaning Scheduled Tasks...
Removing VirusScan Application Folders...
Removing VirusScan Support files...
Removing VirusScan Engine...
Removing VirusScan Support Documentation...
Group record below will be deleted:
Cleaning up...
VirusScan has been successfully uninstalled.
After it was done, all was deleted. Time will tell whether this screws up anything else... (Thank you Time Machine!)