Norton Antivirus has a very long and illustrious reputation for mangling Mac OS X systems, sometimes to the point where a complete reinstall is necessary. Among other things, it installs kernel extensions which are known to cause kernel panics and system freezes; it contains known and documented bugs which can silently corrupt Adobe Photoshop and Adobe InDesign files, destroy a user's ability to authenticate as an administrator, and (on PPC systems) can cause Classic to stop functioning; and Symantec has on at least two occasions now released flawed .dat file updates which erroneously report certain critical Mac OS X files as "viruses." (Deleting these "viruses" causes damage to the system that in some cases renders it unbootable.)
Mackeeper is malware. How to uninstall MacKeeper malware:
http://applehelpwriter.com/2011/09/21/how-to-uninstall-mackeeper-malware/
You may find this User Tip on Viruses, Trojan Detection and Removal, as well as general Internet Security and Privacy, useful:
https://discussions.apple.com/docs/DOC-2435