I have had the 4s for 6 days now and have the phone set the following way:
Wi-Fi: Off at work; On at home
Personal Hotspot: Off all the time (don't need it)
Notifications: Turned on Weather, Mail, Messages, Reminders, Calendar
Locations Services: On; Map widget is enabled for location
Systems Services: All Off
Brightness: 30-40% with Auto On
General>Network: Cell data Off (don't need it all the time)
General>Bluetooth: Off (don't use it much)
General>Restrictions: Ping turned Off
iCloud: Not currently setup
Mail, Contacts, etc: One email account setup for fetch hourly; push is Off; calendars are not synched
Multitasking tray: Generally clear-maybe one or two apps running.
Usage Time: 3 hours 59 minutes
Standby Time: 14 hours 39 minutes
TOTAL TIME: 18 hours 38 minutes
Battery: 49%
Battery seems to drain at the rate of 1% for every 4-5 minutes when actively using the phone to do something. Standby drain (for me) is about 0.95-1.0% per hour.
Based on the standby numbers I could potentially get approx. 100 hours of standby time, or 8.5 hours of "mixed-use" time.
I have had the Personal Hotspot menu item gray out randomly on occasion, suggesting that something in the operating system isn't communicating properly. My impression is that the excessive battery drain issues people are experience, whether during standby or with light to moderate use, is related to the system settings/operating system of the phone.
The phone does get warm with use though; especially when using cellular data or playing games.
Message was edited by: Unshaven