As I noted this morning (10:15 or so), my battery was at 93%... this was just about half an hour after unplugging the phone after a night of charging. After I updated (the phone was still plugged in at that point), I turned on Location Services for Siri, Maps, Reminders, The Weather Channel and Compass. These were what I'd turned off to slow the battery drain prior to 5.0.1. It's now 5:30pm and with those Location Services, Wi-Fi on continuously, Siri and Pushed Email on - pretty much everything I normally would have on, it's at 79%. That's with very little use - 10 emails received, some messages received and sent and a couple internet lookups.
Usage:
Here was my usage at 1:21pm:

And having not plugged it in since disconnecting it this morning, this is the usage at 5:31pm

Now, I'm not sure how exact the usage data is supposed to be, but it just doesn't add up. I have 4 hours and 47 minutes of usage and standby at 1:21pm and I have 9 hours and 23 minutes of usage and standby at 5:31pm. That's a difference of 4 hours, 36 minutes... however, only 4 hours and 10 minutes have passed.
Of course, in taking this screenshot and sending it in an email to my laptop, I lost 1% so, I'm now down to 78% by simply sending an email attachment.
I'm going to completely discharge the battery and recharge to see if that fixes things. On the whole, it looks like standby has been fixed somewhat, but any usage - even the simplest - seems to drain the battery fast. I'm going to also try watching a movie to see how long the battery lasts with that.