Found a fix to mine. With bluetooth. For some reason that I still don't know, the computer didn't detect and install the appropriate device drivers on the first connection to the computer.
Got mine and my wifes iPhone 4s on Tuesday. Hooked my wifes up to itunes 10.5 first. No problems. Installed drivers properly, charging, syncing fine. I go to hook mine up. Nothing happens! Cant see my phone anywhere on my computer. No charging either.
Tried everything all the forums say. Apple support and all. It's now Friday, and I'm pulling my hair out. I was just playing around and turned the bluetooth on on my computer and my 4s to see. It paired successfully. The driver on the other hand did not. Right clicked on my phone in the bluetooth device window, went to properties> hardware> properties> driver. Clicked update driver and voila. Successfull driver install after searching the web for it.
My phone now shows up in iTunes and charges.