iTunes crash every time I tried to launch it

I've got the exact same problem. Updated iTunes to 10.5, did the iOS 5 update, and everything was fine. Then a few days later, this exact same thing started happening to me. I figured it might fix things if I updated to Mac OS X 10.7.2, but after the OS update, there's still no change.

Ok, this is what fixed it for me. I figured out that, for some reason, it was the iTunes Store that was causing the crash. iTunes tries to connect to the store right away and something must've gotten buggered up. I went into System Preferences and went to Network. I disabled my network connection by clicking on my network adapter and changing it from DHCP to None. Once the Internet was disabled, I was able to open iTunes. It gave me an error saying that it couldn't connect to the iTunes Store, which I just clicked away and iTunes continued working. Then I enabled my network connection again in System Preferences and iTunes continued running. I closed iTunes and now it opens fine, even with the Internet connection still on, so somehow, this must've reset some sort of setting and fixed the problem.

Hope this helps.

Thanks, had the same probleme. Now it's solved.

That was a genius and simple solution! I've disabled my iTunes from automatically connectin to the store and hopefully this problem will not arise again. Thank you so much!