Currently Being ModeratedDec 1, 2011 2:36 AM (in response to mbgreenspan)
Go to ~/Library/Caches/com.apple.Safari
Move the Cache.db file from the com.apple.Safari folder.
~ (Tilde) character represents the Home folder.
For LIon: To find the Home folder in OS X Lion, open the Finder, hold the Option key, and choose Go > Library
And disable Resume > How To Disable Lion's 'Resume' Feature - MacRumors.com
And about the beachballs, how much free space on the startup disk? Not enough can slow the drive down.
Right or control click the MacintoshHD icon. Click Get Info. In the Get Info window you will see Capacity and Available. Make sure you have a minimum of 15% free disk space. Freeing Up Hard Disk Space - Mac Guides