I re-installed the 10.7.2 combo. It booted up with a non powered usb 4 port hub but it disabled it. Plugging it out then in again and it works. Looks like the USB firmware has changed somehow in 10.7.2, The hub works on PC's at work no problem, and it worked on the MBP without issue previously. Its not just the non powered hub its a powered hub, and other devices.