I had the same experience ....
After calling Epson they put me on to this driver.
Go to Epson.com and do a search from the scanner driver area (Top Right hand corner)
Type epson13659.dmg to the search Box. Download and install this driver and you will
be back to normal.
This works on my Epson V500 & V600 Scanners
Thanks for the info, revybawb. The page that I found on the Epson site listing the driver you mention is here:
Here's the information about the epson13659.dmg driver from that page:
Intel-based Macs with OS X (v10.4.4 - v10.6.x), Mac OS X (v10.3.9 - v10.5.x)
epson13659.dmg - 17.4MB - posted on 02/03/10
This is a pretty old driver -- February, 2010. It says that it supports only up to Mac v10.5. Are you sure this driver works with Lion?
Has anyone else had luck getting the Epson Perfection V600 to work with Lion?