My wish list:
1. Please let me re-order the adjustment tools. I don't want to hunt up and down the list to do jobs in the order in which I do them, I want the tools in my order.
2. An adjustments history, so with a single click I can go back to any stage. A pro app should expect there to be a lot of editing, it's not just 'Enhance' and done.
3. Local adjustment tools - brushes and gradients.
4. Please make noise reduction work. On the occasions when I need it I export a TIFF to LR5 and apply the noise reduction there (it's fantastic - better than Dfine 2 by far).
5. Whatever else you do, don't dumb it down. iPhoto and Aperture will go in the trash if that happens, and I'll be doomed to the dark side of the Creative Cloud.
Chris