iTunes: How to move [or copy] your music to a new computer [or another drive] - http://support.apple.com/kb/HT4527
do not confuse moving your whole folder and library with moving just media files as in
iTunes for Mac: Moving your iTunes Media folder - http://support.apple.com/kb/HT1449
Quick answer if you let iTunes manage your music: Copy the entire iTunes folder (and in doing so all its subfolders and files) intact to the other drive. Start iTunes with the option key held down and guide it to the new location of the library.
Macworld - How to transfer iTunes libraries between PC and Mac - http://www.macworld.com/article/46248/2005/08/shiftitunes.html
Move an iTunes library from a Windows PC to a Mac - http://www.macworld.com/article/1146958/move_itunes_windows_mac.html
When you sync it syncs the device to the content on the computer's iTunes which in this case was nothing.