There is if the device is managed by a mobile device management software. We use JAMF Nation's Casper Suite and can remotely lock, erase, wipe, push apps and unlock ipads as long as the profile has not been removed, the device at some point connects to the internet and the device has not been reset.
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You are probably already using Exchange ActiveSync to manage devices. You can recover/reset passcodes using the management console. In some cases the user can do this themselves through OWA.
If users forget their password, you can obtain a recovery password using the EMC or the Shell. The recovery password unlocks the device and lets the user create a new password. Users can also recover their device passwords by using Outlook Web App.