Deleting Podcasts from Nano

You must configure them to no longer sync to your device via the iPod's Podcast configuration pane in iTunes.

If you manually manage the iPod's contents, you must manually delete the podcasts from the Nano via the iTunes interface. Choose the small black triangle next to your iPod under Devices to reveal a submenu of content. Locate the podcasts category and select it. Locate the desired podcast, highlight it, and hit the Delete key.

B-rock

Many people say this in the forums. When I do this, absolutely nothing happens.

Connect your ipod to itunes and click on the ipod icon that pops up when you connect it.

Click on "Podcast" under Settings and turn off "Sync Podcasts." Make sure, you have no podcasts on your laptop or computer or if you want to keep some podcasts, select the podcasts your prefer.