hi jajaba, I'm also a professional photographer working most of the time with CS6 and LR4 in my studio and on locations. I have had my rMBP for 2 weeks and I have a BTO 2.3, 16, 256 and it came with a LG screen.
I learned about the IR issue by googling next day after I bought mine and I bought from authorised apple reseller which doesn't offer any return policy (unlike the apple online stroe) even if the equipment has a problem. I did the checkerboard test on pure grey backround and after 6 minutes I was able to see the IR that lasted for another 5 minutes. At first I was sure to replace the screen as even a day after purchase the reseller didn't allow me to exchange or return the product sending me straight to apple service center under warranty. They told me that they will keep it for some 5 days and the ordered replacement may be LG again or Samsung so I decided to hold with the exchenge and see the real life behaviour as I had no other option.
However untill now (2 weeks of intensive use) I haven't seen it even once in real life use. I usually attach the rMBP into a Thunderbold display for the main screen and keep the palletes on the retina (at some 80-90% brightness) or the mail app with strong contrasts of it's interface. It's on for some 8-10 hours and sometimes I have the same image displayed on screen for some half hour or more and then I immidietly swipe the screen to see the grey dots background on the dock and I haven't seen any signs of IR - that's better as at first I was expecting to see it in such situations.
So in my case I can reproduce it intentionally by running the test but untill now I have not seen it in any other real life situation and I'm very aware of it. The PS6 or LR4 has the dark grey interface elements and LR4 has the grey areas arround the images when viewing them in seccond monitor viewport and at that areas I have also not seen any signs of IR after switching from mail screen that was present for some half hour or so.
Now the IR issue bothers me only in the way that I'm often checking to see if I have it and that I'm "waiting for it" in some way - that's very uncomfortable and driving attention - however learning that it does't appear I'm starting to getting used to the rMBP as normal tool. I they find the definitive solution or start replacing Samsungs only then I will go and replace it however now the poor support in this issue doesn't seem to be an optimal solution unless one is bothered by it in real life situations.
As to the config I moved from PC 2 years ago and wouldn't go back due to OS X and overall nice apple experience. The CS6 is overall installed and used by me on default settings and I never tried to reduce it so can't help here. The SSD is used as my primary drive for current work and latest images comming straight from camera. All the projects that has been finised are being moved onto portable USB3 drives (two copies despite the timemachine use) which are still accesible on demand but slower than SSD. One unusual thing in OSX can be FTP server use for image download from the camera. I'm not sure if you are using a WFT wireless transmitter for Canons and if so for me the best and most effective mode is FTP mode as it saves the cameras battery power a lot comparing to regular "always on" mode. In such case the important thing is to enable FTP server support in OS X wich is hidden and done by terminal command only since OS X Lion.