I recently purchased a MacBook Pro running 10.7.4 and Adobe Design & Web Premium CS6. The only problems I am experiencing are with InDesign crashing whenever I open an existing document. I can create new documents in InDesign, but cannot open that document after I close it or any others, even those created in CS5 without crashing the program. Adobe is aware of this issue according to their support line.
What bothers me the most is that Adobe is continuing to sell their software knowing there is an issue and offers no alternative to those who use this software to make their living. Their suggestion was for me to unistall 10.7.4 and install 10.7.3 on my new MacBook Pro. This is of course, unacceptable.
Fortunately I still have CS5 on my iMac that is still running 10.7.3. But for those who do not have this option, it is criminal that Adobe hasn't made some kind of concession to accomodate them until the issue is resolved. I understand Apple's perspective that third-party software must work within their framework, but it seems to me that Apple would also want to take a proactive stance to help resolve the issue since so many people, like myself, make a living with their Macs and Adobe software in unison.
Just my 2 cents, for what it's worth!