Interesting. My wife has been experiencing this exact same issue, but it was with her iMac 27" machine, which is one of the most recent ones that are thinner on the edges. Her original machine before that was an older iMac 27" but I have moved her install over from many Mac's in the past with no issues, so I don't know how old the original install is. Probably goes way back, 3+ years or maybe even more.
Anyway, I thought maybe she had a hardware issue as I had never seen this problem on my many Mac Pro machines, nor on my MacBook Pro, both of which have been updated with fresh OS installs but transferring all the old apps and data using Time Machine backups (or just cloning the hard disk with the Migration Asssistant). So she decided she wanted to be mobile here at work, so I got her the new MacBook Air and a TB monitor, and cloned her drive over to it using the Migration Assistant to the OS that came in the box. Alas, the problem persisted!!
Then to top it all off, I upgraded my MacBook Air to the latest version also and migrated mine over, and suddenly it started doing it also. So I am convinced it is clearly some software that is installed on the machines that gets copied over by the Migration Assistant, and messes things up. The question is exactly WHAT is being copied over that causes the problems? I would much rather figure out he culprit and nuke/reinsall just that, that to have to set her machine up from scratch.
The machine she was using before has now been given to our new designer, and she is using it with a fresh install and all the apps were loaded fresh. So far she has not complained about any problems with it?
So yeah, I think I agree with Tom, it is something getting copied over by the Migration Assistant code. The real question is can we figure out what it is?
I know her computer has Office 2011 installed, iWork '09, Firefox, Adobe Flash and probably not much else. I don't think my Air has much more than Office 2011, iWork '09 and Firefox on it. I wonder if it something to do with the Office install, as I do recall she mentioned a few times it would do it when she was editing Word documents??