I've had the "disappearing cursor" issue for ages now, but just started having a much more serious and harder to deal with problem
Photoshop CS5.1
Mac Pro, OS 10.8.5
Wacom tablet and Apple mouse.
Issue is only happening (as far as I can tell) with Photoshop (possibly in Illustrator and InDesign, but I don't use them as much and the tool/cursor in those work differently to Photoshop).
Cursor sitting on image, my hand not even touching the mouse or wacom pen, and the cursor is "jumping" between the tool selected (hand tool, healing tool, brush tool) and the black arrow select tool.
If I zoom in and attempt to use the healing, clone, tool or brush tool, the "clone from" and "clone to" tools disappear, so I can't tell where I'm working. Same thing with the Brush tool. The round cursor disappears completely so I'm working blind.
I've reset the tool preset, changed between the wacom tablet and an Apple mouse, closed PS, rebooted machine etc, Reset PRAM, pulled Preferences onto desktop, still having the issue. So very different from the "cursor disappears till you cmd-tab to a differnt program or go to the dock cursor issue".
I'm kind of stuck now. Not sure I want to upgrade to Mavericks as I'm not convinced it's an Apple problem and not an Adobe problem, but not sure what to do now.