Tech Harmony's very thorough explanation of how to backup without Spotlight did not work for me. I followed all the steps to the letter and even had tried a few things that he did not mention. Here is what I have done so far (not necessarily in order):
1. Verified/Repaired Permissions on boot drive.
2. Verified/Repaired boot drive (booting into Mountain Lion Recovery Mode).
3. Erased my drive completely and restored only data and applications from backup (no settings).
4. Removed anti-virus.
5. Removed Crash Plan (which I use as a supplementary off-site backup).
6. Deleted all files in /.fseventsd.
7. Deleted the entire Time Machine backup from the network drive (multiple times).
8. Tried tmdiagnose (multiple times).
9. Unloaded Spotlight.
10. Rebuilt Spotlight index (multiple times)
None of these things has worked for me. Here is my config:
Source Machine - MacBook Pro Retina 15" using Thunderbolt Ethernet (WiFi turned off). 10.8.2 with supplemental update.
Desination TM - 2011 Mac MIni Server with Drobo S (2nd Gen) attached via FW800. Running 10.8.2 Server with supplemental update and running Time Machine server.
Every time I run it, TM runs fine for a while and then gets hung up. This is the case even after a fresh rebuild of Spotlight index and erasing the existing TM backup. Best case scenario, it would back up about 200GB of about 650GB and then freeze. Worst case, it would back up only 20GB and then stop. Subsequent backups would also freeze after a period of time. When I say freeze, I mean that neither the number of files nor the size of files changes, after hours go by and even when left overnight.
Right now, I am trying @gitarzysta's suggestion of setting a manual IP address. I am setting manual IP address with DHCP on BOTH the Source Machine and on the Destination TM box. It seems to be running better, but is still in the process. If it completes the current backup, my next step will be to re-enable Spotlight, erase the TM backup again, and try from scratch to see if my machine (restored to normal configuration) will still work.