I've read some of the posts here and elsewhere and cannot find a solution.
I have a brand new MacBook Pro, all maxed out ( not Retina Display ). My previous (and dead) 17" MacBook Pro 2007 model didn't have this problem. My speakers randomly pop and quite often when new windows or apps open or close. I've tried all sorts of supposed solutions with latency settings and cannot fix this.
Could this be due to USB 3? My old MBP had USB 1 and USB 2.
If this is true, I don't really want to spend more money looking for another interface when this one worked great for years.