I have a new 27" iMac and a Lacie 4Big Quadra 16TB USB3 disk array.
I have been trying different things for the past couple of weeks.
The drives function fine fore a couple of hours and then spontaneously eject with the "... improperly ejected ..." message. Pulling the USB3 cable out and plugging back in usually solves the issue, but not always.
I received a replacement Lacie yesterday but it has the exact same issue.
I have tried both units on my rMBP, also exact same issue.
Both machines run ML 10.8.2 and show no software updates.
The iMac is a full clean install, no data, apps or settings on it whatsoever.
I have a support ticket with Lacie, but apart from the replacement unit, got no further info from that.
I just spoke to Apple Support. They say "it is a known issue and Apple is working on an update that should be there in a couple of weeks". He did not know whether it would be part of 10.8.3 or whether the issue was fully root-caused and/or fixed.
I am thinking whether to wait for the update or just exchange the unit for a Thunderbolt one now. Not sure yet.