I have te same scanner. Here are the solutions I posted in the Lion forum earlier this year...
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I have a similar model scanner (LiDE 30). The drivers and the CanoScan software are Power PC. Canon is not supporting these models for Lion. Fortunately, you do have other options...
1) VueScan (http://www.hamrick.com/) - Easy to install and use scanner software (no drivers needed) that will support a large range of scanners. Unfortunately, it's a bit pricey ($40 for a standard license, $80 for a professional license). You can use the unpaid version if you don't mind having watermarks on all of your scans.
2) TWAIN SANE (http://www.ellert.se/twain-sane/) - I chose this option. It's free, but it is a bit more cumbersome to install. The installation packages, essentially, create a driver that will allow your computer to recognize your device. Once installed, OS X's built-in "Image Capture" app will become your scanner's primary interface.
Do note, that with either option, you will no longer be able to use the buttons on the scanner to execute functions (no fix for this, sorry). You ask me, that's a small price to pay for continued usability.