Grapher.app in OS X Utilities is excellent for that : entering data from Numbers Excel etc. into a Grapher "Point Set", plotting all your data, computing and plotting a regression curve linear or exponential or polynomial.
Unfortunately there is not a single word about point sets and regression in the Grapher Help.
So, suggest you download (free) "Instruction for Use - Grapher on web site
http://y.barois.free.fr/grapher/Documentation.html
and go to page 31 to 37, "Initiation > Lesson 6 : Treating a point set (Regression curve), and also page 68, "Appendix 1. Points sets : from speadsheets to Grapher".
If you try Grapher's regression curves, please tell us about the manual above : useful or not, too easy or difficult, readable or not etc.
Thank you.
YB24
PS. Documentation about Grapher is also here : Google "Apple Grapher" > http://en.wikipedia.org/wiki/Grapher > Article > Talk > Grapher 1.1 to 2.3 (French and English) (11th september 2012)