hat I still do to stop a drain is turn the iphone then switch it back on again
this is what i did and settings I use:
1/ Restore and set up as new iphone then add all my apps manually ( a real pain I know ) and I do this on my PC and dont use icloud.
These are my settings that I use and it works for me I take iphone off charge at 0700 and back on at 2100hrs, normally about 75 to 70% left of battery.
1/ Wifi off ( except when im at home then i use it all the time)
2/ i dont use bluetooth
3/ personal hotspot off
4/notifaction centre i only have mail messages phone omnifocus calvectica apps in there all other items are not there and do notify at all
5/siri raise to speak off and time supporrt set to off
6/celluar 3g off except if i use it
7/auto lock 1 minute
8/brightness auto brightness off backlight at 3/4 full
9/location services off except when i use them
10/icloud logged out
11/ mail fetch hourly push off advanced set to fetch
12/ face time mobile data off
13/ itunes store mobile data off
14/ podcasts auto download mobile data off
15/ipod equaliser off
These are what I use and they worl for me hope this helps