Multiple IPs and firewalls

I'm wondering if it's possible to create multiple firewalls in Mountain Lion server. I have four IP addresses on one server, all on the same LAN, and I want to restrict specific traffic to specific TCP/UDP ports (e.g. only mail ports on IP X, web services on IP Y, and VPN services on IP Z, etc.).

Is it possible to create multiple firewalls on each port so that I can restrict network traffic in this manner? Or is there a better way to do this from the start?

Thanks!