iTunes could not copy [song title] because an unknown error occurred (-54)

For the past month or so I've been unable to sync it with iTunes. When I do, it starts but after a few hundred songs, I get the error that "itunes could not copy [song title] because an unknown error occurred (-54). When I click OK, it then says "synching" but nothing is actually happening, and the only way to even get my browser working again is to restart my pc. I have deleted the song in question, but it will just do it again with a different song. I have uninstalled and reinstalled iTunes to the most recent version, reset the iPod Touch numerous times, As well as deleting the iTunes files off of my computer and reloading all the muisc to it. To make things more interesting, it does all of this on my laptop pc as well as my desktop. Now. all of this may have started before upgrading the software, but that was the last time in months that I tried to sync it, so there may or not be a correlatoin there.

Any help is greatly appreciated, and thanks in advance.